MVP antibody

Catalog No. ABIN5708257

This anti-MVP antibody is a Rabbit Polyclonal antibody detecting MVP in WB, FACS, ELISA and IHC (p). Suitable for Human, Mouse and Rat.

Quick Overview for MVP antibody (ABIN5708257)

Target: MVP (Major Vault Protein (MVP))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MVP antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-MVP Antibody

Purification: Antigen affinity purified

Immunogen: A recombinant human protein corresponding to amino acids A2-H259 was used as the immunogen for the MVP antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the MVP antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL, IHC (FFPE): 1-2 μg/mL,FACS: 1-3 μg/10^6 cells, Direct ELISA: 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the MVP antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for MVP

Target: MVP (Major Vault Protein (MVP))

Alternative Name: MVP

Background: Major vault protein is a protein that in humans is encoded by the MVP gene. This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene.

UniProt: Q14764